AgreenSkills session, year: 2nd session, 2014
Receiving laboratory: LIPM Plant-Microbe Interactions Toulouse, France
Country of origin : United Kingdom
Symbiotic nitrogen fixation is of major importance for sustainable agriculture worldwide. Legume plants have the unique ability of acquiring nitrogen by establishing symbiotic associations with soil-borne bacteria. The rhizobia-legume endosymbiotic interaction involves major and specific reprogramming of host cells as the infecting microbe progresses through several root cell layers to ultimately reach a newly formed plant organ, where nitrogen fixation takes place. This project will investigate how spatial signaling is regulated during infection and whether direct cell-to-cell communication influences the host plant infection reprogramming.
I studied Biology at the University of Bonn and finished 2005 with a Diploma thesis at the Institute of Cellular and Molecular Botany in Bonn using fluorescent protein reporters coupled with in vivo microscopy to study cellular processes in plant cells. Fascinated by the possibility to look inside plants and to visualize their extremely fast intracellular responses, I continued from 2006-2009 for my PhD working on mitogen-activated-protein kinase (MAPK) signaling and its contribution to the remodeling of cytoskeletal elements during plant development, thereby discovering the important role of MAPKs in the regulation of microtubule structure and dynamics during cell elongation and cell division in Arabidopsis thaliana. For my first PostDoc at 2010, I moved to the UK at The Sainsbury Laboratory in Norwich to study the intracellular dynamics of an important bacterial immune receptor in plants, setting up an automated high throughput imaging method to identify the intracellular trafficking pathway of this protein. My primary research interest is to understand how different signal perception can lead to specific and well organized intracellular changes in plant cells, thereby trying to develop or to improve in vivo imaging methods to study signaling dynamics in living cells.
Beck, M., Wyrsch, I., Strutt, J., Wimalasekera, R., Webb, A., Boller, T. and Robatzek, S. (2014) Expression patterns of FLAGELLIN SENSING 2 map to bacterial entry sites in plant shoots and roots. J Exp Bot 65(22):6487-98
Beck M, Zhou J, MacLean D and Robatzek S, (2012) Spatio-temporal cellular dynamics of the Arabidopsis flagellin receptor reveal activation status-dependent endosomal sorting Plant Cell.;24(10) 4205-19
Beck M, Komis G, Ziemann A, Menzel D and Šamaj J (2011) Mitogen-activated protein kinase 4 is involved in the regulation of mitotic and cytokinetic microtubule transitions in Arabidopsis thaliana, New Phytologist 189(4):1069-83.
Beck M, Komis G, Müller J, Menzel D, Samaj J. (2010) Arabidopsis homologs of nucleus- and phragmoplast – localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization. Plant Cell 22(3):755-71.
2008-2009 Postgraduate Scholarschip of University Bonn
2010_-2012 DFG PostDoctoral Fellowship
2015-2017 TULIP LabEx PostDoctoral Fellowship
2015-2017 AgreenSkills Fellowship